Hydroxvapatite, sodium pyrophosphate, carbamide peroxide를 배합한 불화물배합세치제의 치은염완화 효과와 법랑질표면경도 및 명도변화에 관한 연구
Effect of the dentifrice containing hydroxyapatite, sodium pyrophosphate and carbamide peroxide on the reduction of gingivitis, the change ot microhardness and brightness on tooth enamel
소속 상세정보
마득상/Deuk Sang Ma
박덕영/정세환/정상효/백대일/문혁수/김종배/마득상/박덕영/Deok Young Park/Se Hwan Jung/Sang Ho Jung/Dai Il Park/Hyock Soo Moon/Johng Bai Kim/Deuk Sang Ma/Deok Young Park
KMID : 0355419980220010001
Abstract
결론
저자들은 0.76% 일불소인산나트륨, 3% carbamide peroxide를 배합한 실험세치제의 치은
염 완화효과를 연구하기 위하여, 20대 남녀 30명을 대상으로 실험세치제와 대조세치제를 각
각 4주간 사용하게 하여 실험세치제의 치은염완화효과를 비교 검토하였고, 0.76% 일불소인
산나트릅, 3% carbamide peroxide를 배합한 실험세치제1과 0.38% 일불소인산나트륨, 0.11%
불화나트륨, 0.5% hydroxyapatite, 3.4% pyrophosphate를 배합한 실험세치제2의 법랑질표면
경도에 미치는 영향을 연구하기 위하여, 치아우식병소가 없는 우치시편을 채취하여 본 실험
에 적합하게 제작된 전동잇솔질기로 20,000행정의 잇솔질을 한후, 실험세치제의 잇솔질 전후
법랑질표면경도변화를 비교 검토한 결과, 다음과 같은 결론을 얻었다.
1. 0.76% 일불소인산나트릅과 3% carbamide peroxide를 배합한 실험세치제 1은 대조세치
제보다 통계적으로 유의하게 치은염을 완화시켰다(P<0.05).
2. 0.76% 일불소인산나트륨과 3% carbamide peroxide를 배합한 실험세치제1과 대조세치
제의 잇솔질전후법랑질표면경도 변화는 통계적으로 유의한 차이가 인정되지 않았다
(P<0.05).
3. 0.38% 일불소인산나트륨과 0.11% 불화나트륨과 0.5% hydroxyapatite 및 3.4% sodium
pyrophosphate를 배합한 실험세치제2와 대조세치제의 잇솔질전후법랑질표면경도 변화는 통
계적으로 유의한 차이가 인정되지 않았다(P<0.05).
4. 0 76% 일불소인산나트륨과 5% carbamide peroxide를 배합한 실험세치제1은 대조세치
제보다 착색후잇솔질전후의 법랑질표면명도변화에 통계적으로 유의한 차이가 나타났다
(P<0.05).
5. 0.38% 일불소인산나트륨과 0.11% 불화나트륨과 0.5% hydroxyapatite 및 3.4% sodium
pyrophosphate를 배합한 실험세치제2는 대조세치제 보다 착색후잇솔질전후의 법랑질표면명
도 변화에 통계적으로 유의한 차이가 나타났다(P<0.05).
50 adult male and female subjects completed 4-week, double-blind clinical study
comparing the effect on gingivitis of the dentifrice containing 0.76% sodium
monofluorophosphate and 3.0% carbamide peroxide. Subjects were divided by two
balanced groups according to baseline gingivitis scores. Gingivitis index was scored by
Loe-Silness' Gingival index.
Microhardness of tooth enamel of the dentifrice containing 0.76% sodium
monofluorophosphate and 3.0% carbamide peroxide and the dentifrice containing 0.38%
sodium monofluorophosphate, 0.11% sodium fluoride, 0.5% hydroxyapatite, and 3.4%
tetrasodium pyrophosphate was measured by microhardness tester (Shimadzu corporation
Model, HMV-2000 No. 33100410, Japan) before and after 20,000 strokes with brushing
machine.
Brightness of tooth enamel of the dentifrice containing 0.76% sodium
monofluorophosphate and 3.0% carbamide peroxide and the dentifrice containing 0.38%
sodium monofluorophosphate, 0.11% sodium fluoride, 0.5% hydroxyapatite, and 3.4%
tetrasodium pyrophosphate was measured by colorimeter before and after 200 strokes
with brushing machine.
The obtained results were as follows :
1. The dentifrice containing 0.76% sodium monofluorophosphate and 3.0% carbamide
peroxide was shown to provide a statistically significant reduction in gingivitis than the
control dentifrice after 4 weeks(P<0.05).
2. There was no statistical significant change in the microhardness between the
dentifrice containing 0.76% sodium monofluorophosphate and 3.0% carbamide peroxide
and the control dentifrice(P≥0.05).
3. There was no statistical significance of the microhardness changes between the
dentifrice containing 0.38% sodium monofluorophosphate, 0.11% sodium fluoride, 0.5%
hydroxyapatite, and 3.4% tetrasodium pyrophosphate and the control dentifrice(P≥0.05).
4. There was statistical significance of the brightness changes between the dentifrice
containing 0.76% sodium monofluorophosphate and 3.0% carbamide peroxide and the
control dentifrice(P<0.05).
5. There was statistical significance of the brightness changes between the dentifrice
containing 0.38% sodium monofluorophosphate, 0.11% sodium fluoride, 0.5%
hydroxyapatite, and 3.4% tetrasodium pyrophosphate and the control dentifrice(P<0.05).
키워드
hydroxyapatite; pyrophosphate; carbamide peroxide; 법랑질표면경도; 법랑질표면명도변화; 세치제; hydroxyapatite; pyrophosphate; carbamide peroxide; microhardness; brightness;
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